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Home - Products - Metabolic Enzyme/Protease - Lipase - JW 642

JW 642

CAS No. 1416133-89-5

JW 642 ( —— )

Catalog No. M26726 CAS No. 1416133-89-5

JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL)

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 31 Get Quote
10MG 50 Get Quote
25MG 98 Get Quote
50MG 177 Get Quote
100MG 332 Get Quote
200MG 494 Get Quote
500MG Get Quote Get Quote
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Biological Information

  • Product Name
    JW 642
  • Note
    Research use only, not for human use.
  • Brief Description
    JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL)
  • Description
    JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).(In Vitro):MAGL inhibitor JW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s: 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively).
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Lipase
  • Recptor
    HPPD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1416133-89-5
  • Formula Weight
    462.4
  • Molecular Formula
    C21H20F6N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC(F)(F)C(OC(=O)N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rocaboy-Faquet E, et al. A novel amperometric biosensor for ?-triketone herbicides based on hydroxyphenylpyruvatedioxygenase inhibition: A case study for sulcotrione. Talanta. 2016;146:510-6.
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